Move forward twenty-eight weeks. All the infected are dead from starvation, clean up has begun and civilians are returning to a cleared out section that is under heavy military guard.
The kids are reunited with their father, who just happens to be in charge of maintaining the building they will be living in. This is significant later on because his key card is an all access card. All returnees are told NOT to leave the secured area for any reason, so of course the two kids sneak out the first chance they get. They are found and returned to the secured area, along with their mother who they happen to find living in their old house.
This really bugged me. I can buy that there might be people immune to the virus. After all, this happens all the time in nature.
But, the zombies are rage fueled creatures that literally tear apart their victims. So, OK, she doesn't become a zombie, but why isn't she in multiple pieces? Anyway, thanks to the aforementioned key card and lackluster security why does a civilian have access to the room where they are keeping the mother while they determine if she has the virus is beyond me , she ends up infecting the father and all hell breaks loose.
At this point, the movie becomes pretty much non-stop action which is good because character development has been weak. Actually, I just didn't care about the characters. The kids manage to escape along with some cannon fodder, er, other people and are trying to flee the city.
The military is killing everyone including civilians in an attempt to stave off the spread of the virus. The small band moves through the city hunted by humans and military alike. There's hints of deeper themes, but unlike the original movie, the sequel can't seem to pull them off.
We end up with the inevitable showdown between the two kids and their diseased dad. Needless to say, dad gets blown away but not before biting the son, who turns out to have inherited the immunity gene.
He doesn't become a zombie, but is now a carrier like his mother. The movie ends with a glimpse of the future - specifically, as shown in text on the screen, 28 Days after the kids are rescued. Stone sees the blood and dead soldiers. He executes Code Red and has the facility shut down. The doors to the facility are locked and the power is shut down, switching to the back-up power. Stone goes to the command center and gives orders to his troops.
The kids are locked in the room, waiting for the soldier to return. The infected soldier bursts into the room and pounds on the glass separating them. His head is blown off by Scarlet, who frees the kids and leads them through the facility. The soldiers lock the civilians in the basement, chaining the door shut to protect them from the infected.
Andy, scared and alone, sits by himself near the back of the room. Don grabs a civilian and vomits blood onto him, and the infection quickly spreads throughout the basement while everyone panics in the dark. Andy manages to climb into an air vent and stays there as he hears people being killed and infected. The civilians break out of the room and run up the stairs, but are chased after by the infected.
They make it outside, and Stone orders his men to only aim for the infected. Realizing this, Stone orders the soldiers to kill everyone. The snipers and soldiers proceed to slaughter the civilians and the infected around them. Andy climbs out of the air vent and ends up right in the middle of the bloodbath. Andy runs to the supermarket, where several other people are hiding. Doyle leaves his position and goes after the boy. Andy walks through the darkened store and is startled by everyone he encounters.
Luckily, he finds Tammy inside with Scarlet and is reunited with them. Knowing that everyone will be wiped out due to Code Red, Doyle volunteers to lead the survivors to safety. Doyle, Scarlet, Andy, Tammy, and a couple of others leave the store and enter the empty streets. Doyle tells everyone to stick together, and they run throughout the city while Andy gets a glimpse of Don following them.
They set up a rendezvous point, and the survivors are fired upon by a sniper. The sniper kills two or three people, and Scarlet is shot in the leg. Knowing the time limit they have, Doyle tells a survivor to run in a zigzag so that he can kill the sniper when he gives away his position.
The survivor is too afraid to do it, and Andy runs out in the open. The sniper tries to shoot him, but Doyle shoots the sniper in the head. The remaining survivors run to a tunnel in the subway and brace themselves. The city is firebombed, filling the streets with explosions and fire. The infected are blown away, but Don manages to survive the attack.
The explosions destroy the cameras set up around the city. The survivors run out of the subway station just before it explodes. As he sits down, Stone sees that the only camera still working is the one outside of the command center. Hopeful with relief, Jim asks the man to open the door and help them out, but is only met with cold refusal, as the man states that he does not wish to get emotionally attached to people fated to die soon.
After numerous failed attempts of trying to coax the man out of the room, Jim brings Hannah near the door, explaining how Frank will die if not injected with a cure soon. This is where the narrative integrity of the alternative ending of 28 Days Later falters, as both Boyle and Garland were unable to add the element of plausibility to the blood transfusion storyline.
Apart from being logically flawed, it also hampers the suspension of disbelief, raising more questions about the nature of the virus that are left unanswered. Nevertheless, Jim agrees to make the transfusion, and the film ends with a now-revived Frank and an infected Jim strapped to the operating table, thrashing in unbearable agony.
The reunion is cut short when the US military , having been sent to bring Tammy and Andy back to District One, arrive and take them and Alice back to the green zone, where Alice is separated from the kids and the three are detained. During medical inspection of Alice, Scarlet is about to do a blood test and is trying to ask Alice how she stayed alive out in the post-outbreak country, when she notices an old bite scar on Alice's arm and fears Alice may be infected.
Meanwhile, Don goes to a detained Tammy and Andy to take them home, but the kids are furious with their father for lying to them about their mother's fate and demand to know the truth about what really happened. Guilty over abandoning his wife, Don leaves and slips past the military security to go to Alice in the isolation room. As Don sneaks in to see Alice, Scarlet's tests on Alice's blood confirm that she is infected with the Rage virus, but is not suffering any of the virus' symptoms due to a natural immunity caused by a genetic abnormality - making Alice an asymptomatic carrier who is herself immune to the virus' symptoms, but still carries the virus and can pass it on to others.
Scarlet wants to keep Alice alive for more tests in hopes of finding a key to immunisation against the Rage virus from Alice's blood, but Stone wants to have Alice killed to ensure she can't cause another outbreak of infection.
In the isolation room, Don begs Alice to forgive him for abandoning her, which she seemingly does. The infected Don brutally beats Alice to death, before escaping into District One, attacking and infecting or killing anyone he comes across.
Upon learning infection is spreading, Stone and the other generals move to a safety bunker and execute a District One lockdown called Code Red. As the Rage virus spreads and chaos takes hold, when the spread reaches the detainment area where Tammy and Andy are, Scarlet comes and rescues the kids and tries to get them evacuated to safety as top-priority figures. However, in the chaos, Andy gets separated from Scarlet and Tammy and is herded with District One's other civilians into a safe room garage where the soldiers lock them all inside as the green zone's power cuts out.
As District One's military forces mobilise against the outbreak, in the garage where Andy and the civilians are locked in, the infected Don breaks into the garage as a horrified Andy watches and attacks the civilians, causing the infection to massively and virulently spread among the civilians there in a domino effect and quickly infecting dozens - hundreds. In the panic, the civilians break out of the garage and flee into the streets, while Andy escapes from the infected through the ventilation systems.
In the streets of District One, Doyle and the other rooftop snipers are initially ordered to shoot only infected, but as the infection continues to spread and it becomes harder to tell the infected from uninfected, they're ordered to kill everyone in sight.
Andy escapes from the chaos and infected into a warehouse where other survivors are holed up as the military massacre everyone, while Doyle - unable to comply with kill-all order - abandons his post and joins the survivors in the warehouse.
There, Andy reunites with Scarlet and Tammy and sadly informs his sister of how their father is one of the infected, and Doyle offers the kids, Scarlet and three other survivors there to escape the chaotic green zone with him before the military inevitably exterminates them with the infected. Doyle subsequently leads the group through the empty streets towards the District One perimeter, trying to fight off snipers shooting at them along the way although two of the three other survivors are killed along the way.
Just as the Air Cavalry arrive to firebomb District One, Doyle, Andy, Scarlet, Tammy and Sam the remaining other survivor escape over the District One perimeter just as the green zone is firebombed and destroyed and thousands there killed. The generals watch District One burn from in their bunker, but Stone also sees that a large number of infected have survived the firebombing and are escaping into London.
As dawn arrives, Doyle and the other four survivors travel across an empty and dilapidated London to Regent's Park to be airlifted to safety by Flynn when he comes to Doyle. As Scarlet and Doyle discuss how they ended up turning against the military and how Scarlet saved Tammy and Andy because she believes they may have inherited their mother's immunity to the symptoms of the Rage virus, Tammy and Andy think about all that has happened, and Tammy admis she doesn't believe Alice has survived this time.
Flynn warns Doyle over the radio of the surviving infected loose in London, and a large horde of the infected then arrive at Regent's Park as Flynn flies to the Park for Doyle by helicopter.
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